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Joseph Lennox

Contact Information

Office: 217 McGregor Hall

Phone: 937-319-0078

Email: jlennox@antiochcollege.edu

Visiting Assistant Professor of Organic Chemistry

Dr. Joseph Lennox invested 13 years working in the biopharmaceutical industry designing drug substances useful for a variety of therapeutic indications: asthma, bladder cancer, cerebral ischemia, cystic fibrosis, epilepsy, hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), inflammation, migraine, neuroprotection, non-insulin dependent diabetes mellitus (NIDDM), and urge urinary incontinence. His biopharmaceutical career emphasized applications of medicinal chemistry to biochemistry, immunology, ion channel modulation, and molecular biology. While in industry, he trained personnel at the BS, MS and PhD levels.

Joseph has consulted for the biotechnology and legal sectors since 2007. He conducted private educational research from 2010-2012 to determine why students struggle through organic chemistry. In January 2013, he joined the University of California, San Diego (UCSD) for a one-year appointment as a Lecturer in Chemistry, delivering courses for both science and non-science majors. In January 2014 he migrated to San Diego county community colleges (Palomar College and Mira Costa College) to conduct research focusing on applications of learner-centered teaching and metacognition in chemistry education. While at Palomar, he was heavily involved in the STEM Instructor Mentorship Program where he provided guidance to students in honing of career interests, transitioning to a four-year college, pursuit of internships/scholarships, and fostering pursuit of scientific careers by women, the economically and socially disadvantaged, and the ethnically underrepresented. He was an Assistant Professor of Chemistry at the Oregon Institute of Technology during 2015-2016. Recently, he was invited to join the Antioch College Science Division as a Visiting Assistant Professor of Organic Chemistry.

Although passionate about teaching and mentoring science majors, Joseph enjoys creating themed-based courses in chemistry and interdisciplinary courses in science for non-science majors. His educational philosophy is highly learner-centered, and incorporates active learning into courses whenever possible.

EDUCATION

  • Postdoctoral Fellow, Department of Chemistry, University of California – Berkeley

  • PhD, Department of Chemistry, University of Wisconsin – Madison

  • BA, Department of Chemistry, La Salle University

COURSES

  • CHEM 205 Organic Chemistry I

  • CHEM 330 Organic Chemistry II

  • NDE 305 Learner-Centered Teaching

  • SCI 101 Foundational Topics in Science: From Atoms to Pharmaceutical Ethics

  • SCI 370 Special Topics in Science: Medicinal Chemistry

SCHOLARLY ACTIVITIES

SELECTED PUBLICATIONS

  • Xiang, A.X.; Webber, S.E.; Kerr, B.; Rueden, E.J.; Lennox, J.R.; Haley, G.J.; Wang, T.; Ng, J.; Herbert, M.; Clark, D.L.; Banh, V.; Li, C.; Fletcher, S; Steffy, K.; Bartkowski, D.; Bauman, L.; Averett, D.R.. “Discovery of ANA975: An Oral Prodrug of the TLR-7 Agonist Isatoribine”  Nucleosides, Nucleotides & Nucleic Acids 2007, 26(6-7), 635-640.

  • Butera, J.A.; Jenkins, D.J.; Lennox, J.R.; Sheldon, J.H.; Norton, N.W.; Warga, D.; Argentieri, T.M. “Synthesis and Bladder Smooth Muscle Relaxing Properties of Substituted 3-Amino-4-aryl-(and aralkyl)cyclobut-3-ene-1,2-diones. Bioorg. & Med. Chem. Lett. 2005, 15(10), 2495-2501.

  • Butera, J.A.; Antane, S.A.; Hirth, B.; Lennox, J.; Sheldon, J.H.; Norton, N.W.; Warga, D.; Argentieri, T.M. “Synthesis and Potassium Channel Opening Activity of Substituted 10H-Benzo[4,5]furo[3,2-b]indole and 5,10-Dihydroindeno[1,2-b]indole-1-Carboxylic Acids”. Bioorg. Med. Chem. Lett., 2005, 11, 2093-2097.

SELECTED US PATENTS

  • Webber, S.D.; Haley, G.J.; Lennox, J.R.; Xiang, A.X.; Rueden, E.J. “3,5-Disubstituted and 3,5,7-Trisubstituted-3H-oxazolo and 3H-Thiazolo[4,5-D]pyrimidin-2-one Compounds and Prodrugs Thereof”, US 8883758.

  • Haley, G.J.; Lennox, J.R.; Xiang, A.X.; Webber, S.D. “Prodrugs of 5-Amino-3-(3’-deoxy-b-D-ribofuranosyl)-thiazolo[4,5-D]pyrimidine-2,7-dione”, US 7709448.

  • Averett, D.R.; Webber, S.E.; Lennox, J.R.; Rueden, E.J.; Clark, D.L.; Xiang, A.X. “3-b-D-Ribofuranosyl-thiazolo[4,5-d]pyrimidine Nucleosides and Uses Thereof”, US 7943759.